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CpG-creating mutations are costly in many human viruses

Mutations can occur throughout the virus genome and may be beneficial, neutral or deleterious. We are interested in mutations that yield a C next to a G, producing CpG sites. CpG sites are rare in eukaryotic and viral genomes. For the eukaryotes, it is thought that CpG sites are rare because they ar...

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Detalles Bibliográficos
Autores principales: Caudill, Victoria R., Qin, Sarina, Winstead, Ryan, Kaur, Jasmeen, Tisthammer, Kaho, Pineda, E. Geo, Solis, Caroline, Cobey, Sarah, Bedford, Trevor, Carja, Oana, Eggo, Rosalind M., Koelle, Katia, Lythgoe, Katrina, Regoes, Roland, Roy, Scott, Allen, Nicole, Aviles, Milo, Baker, Brittany A., Bauer, William, Bermudez, Shannel, Carlson, Corey, Castellanos, Edgar, Catalan, Francisca L., Chemel, Angeline Katia, Elliot, Jacob, Evans, Dwayne, Fiutek, Natalie, Fryer, Emily, Goodfellow, Samuel Melvin, Hecht, Mordecai, Hopp, Kellen, Hopson, E. Deshawn, Jaberi, Amirhossein, Kinney, Christen, Lao, Derek, Le, Adrienne, Lo, Jacky, Lopez, Alejandro G., López, Andrea, Lorenzo, Fernando G., Luu, Gordon T., Mahoney, Andrew R., Melton, Rebecca L., Nascimento, Gabriela Do, Pradhananga, Anjani, Rodrigues, Nicole S., Shieh, Annie, Sims, Jasmine, Singh, Rima, Sulaeman, Hasan, Thu, Ricky, Tran, Krystal, Tran, Livia, Winters, Elizabeth J., Wong, Albert, Pennings, Pleuni S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245597/
https://www.ncbi.nlm.nih.gov/pubmed/32508375
http://dx.doi.org/10.1007/s10682-020-10039-z