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High fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice

BACKGROUND: High fat diet impact transcription of hepatic genes responsible for drug metabolism and pharmacokinetics. Until now, researches just focused on a couple specific genes without a global profile showing. Age-dependent manner was also not noted well. This study aims to investigate the high...

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Detalles Bibliográficos
Autores principales: He, Yuqi, Yang, Tao, Du, Yimei, Qin, Lin, Ma, Feifei, Wu, Zunping, Ling, Hua, Yang, Li, Wang, Zhengtao, Zhou, Qingdi, Ge, Guangbo, Lu, Yanliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245748/
https://www.ncbi.nlm.nih.gov/pubmed/32489392
http://dx.doi.org/10.1186/s12986-020-00456-w