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TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes

BACKGROUND: Mesendodermal formation during early gastrulation requires the expression of lineage-specific genes, while the regulatory mechanisms during this process have not yet been fully illustrated. TATA box-binding protein (TBP) and TBP-like factors are general transcription factors responsible...

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Detalles Bibliográficos
Autores principales: Liang, He, Zhang, Peng, Bai, Hua-Jun, Huang, Jijun, Yang, Huang-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245780/
https://www.ncbi.nlm.nih.gov/pubmed/32448362
http://dx.doi.org/10.1186/s13287-020-01711-w