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Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells

BACKGROUND: Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural programmed cell death (apoptosis). Tumor and embryonic cells are used as in v...

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Detalles Bibliográficos
Autores principales: El-Obeid, Adila, Alajmi, Hala, Harbi, Mashael, Yahya, Wesam Bin, Al-Eidi, Hamad, Alaujan, Monira, Haseeb, Adil, Trivilegio, Thadeo, Alhallaj, Alshaimaa, Alghamdi, Saleh, Ajlouni, Abdul-Wali, Matou-Nasri, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245827/
https://www.ncbi.nlm.nih.gov/pubmed/32448225
http://dx.doi.org/10.1186/s12906-020-02944-1