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Hyperthermia depletes Oct4 in mouse blastocysts and stem cells

Temperature is an important microenvironmental factor that functions epigenetically in normal embryonic development. However, the effect of hyperthermia in the stem cells is not fully understood. Oct4 is a tightly regulated master regulator of pluripotency maintenance in stem cells and during early...

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Detalles Bibliográficos
Autores principales: Cheng, Mo-bin, Wang, Xue, Huang, Yue, Zhang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245852/
https://www.ncbi.nlm.nih.gov/pubmed/32448390
http://dx.doi.org/10.1186/s13287-020-01715-6