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Hyperthermia depletes Oct4 in mouse blastocysts and stem cells
Temperature is an important microenvironmental factor that functions epigenetically in normal embryonic development. However, the effect of hyperthermia in the stem cells is not fully understood. Oct4 is a tightly regulated master regulator of pluripotency maintenance in stem cells and during early...
Autores principales: | Cheng, Mo-bin, Wang, Xue, Huang, Yue, Zhang, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245852/ https://www.ncbi.nlm.nih.gov/pubmed/32448390 http://dx.doi.org/10.1186/s13287-020-01715-6 |
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