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PARP inhibitor olaparib sensitizes esophageal carcinoma cells to fractionated proton irradiation

Proton beam therapy (PBT) combined with chemotherapy, such as cis-diamminedichloroplatinum (II) (CDDP) and 5-fluorouracil (5-FU), has been employed as an alternative approach to improve clinical outcomes. PBT has been reported to be effective against esophageal cancer. However, apart from 5-FU and C...

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Detalles Bibliográficos
Autores principales: Kageyama, Shun-ichiro, Junyan, Du, Hojo, Hidehiro, Motegi, Atsushi, Nakamura, Masaki, Tsuchihara, Katsuya, Akimoto, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246074/
https://www.ncbi.nlm.nih.gov/pubmed/31976528
http://dx.doi.org/10.1093/jrr/rrz088