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Topology-Dependent Interference of Synthetic Gene Circuit Function by Growth Feedback

Growth-mediated feedback between synthetic gene circuits and host organisms leads to diverse emerged behaviors, including growth bistability and enhanced ultrasensitivity. However, the range of possible impacts of growth feedback on gene circuits remains underexplored. Here, we mathematically and ex...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Li, Jiao, Melendez-Alvarez, Juan, Chen, Xingwen, Sochor, Patrick, Goetz, Hanah, Zhang, Qi, Ding, Tian, Wang, Xiao, Tian, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246135/
https://www.ncbi.nlm.nih.gov/pubmed/32251409
http://dx.doi.org/10.1038/s41589-020-0509-x