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A Novel Anti-Kv10.1 Nanobody Fused to Single-Chain TRAIL Enhances Apoptosis Induction in Cancer Cells

Antibody-based therapies hold promise for a safe and efficient treatment of cancer. The identification of target tumor cells through a specific antigen enriched on their surface and the subsequent delivery of the therapeutic agent only to those cells requires, besides the efficacy of the therapeutic...

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Detalles Bibliográficos
Autores principales: Hartung, Franziska, Krüwel, Thomas, Shi, Xiaoyi, Pfizenmaier, Klaus, Kontermann, Roland, Chames, Patrick, Alves, Frauke, Pardo, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246340/
https://www.ncbi.nlm.nih.gov/pubmed/32528281
http://dx.doi.org/10.3389/fphar.2020.00686