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Expression patterns of CD28 and CTLA‐4 in early, chronic, and untreated rheumatoid arthritis

BACKGROUND: T‐cell activation pathways have been proposed as trigger mechanisms in the pathogenesis of rheumatoid arthritis (RA). CD28 and CTLA‐4 play major roles in regulating the stimulatory and inhibitory co‐signals in T cells. OBJECTIVE: To analyze the association between soluble and surface exp...

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Detalles Bibliográficos
Autores principales: García‐Chagollán, Mariel, Ledezma‐Lozano, Iris Yolanda, Hernández‐Bello, Jorge, Sánchez‐Hernández, Pedro Ernesto, Gutiérrez‐Ureña, Sergio Ramón, Muñoz‐Valle, José Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246387/
https://www.ncbi.nlm.nih.gov/pubmed/31907973
http://dx.doi.org/10.1002/jcla.23188