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Sildenafil Reduces Expression and Release of IL-6 and IL-8 Induced by Reactive Oxygen Species in Systemic Sclerosis Fibroblasts

Oxidative stress linked to vascular damage plays an important role in the pathogenesis of systemic sclerosis (SSc). Indeed, vascular damage at nailfold capillaroscopy in patients with Raynaud’s Phenomenon (RP) is a major risk factor for the development of SSc together with the presence of specific a...

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Detalles Bibliográficos
Autores principales: Di Luigi, Luigi, Sgrò, Paolo, Duranti, Guglielmo, Sabatini, Stefania, Caporossi, Daniela, Del Galdo, Francesco, Dimauro, Ivan, Antinozzi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246497/
https://www.ncbi.nlm.nih.gov/pubmed/32365773
http://dx.doi.org/10.3390/ijms21093161