Cargando…

Sildenafil Reduces Expression and Release of IL-6 and IL-8 Induced by Reactive Oxygen Species in Systemic Sclerosis Fibroblasts

Oxidative stress linked to vascular damage plays an important role in the pathogenesis of systemic sclerosis (SSc). Indeed, vascular damage at nailfold capillaroscopy in patients with Raynaud’s Phenomenon (RP) is a major risk factor for the development of SSc together with the presence of specific a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Luigi, Luigi, Sgrò, Paolo, Duranti, Guglielmo, Sabatini, Stefania, Caporossi, Daniela, Del Galdo, Francesco, Dimauro, Ivan, Antinozzi, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246497/ https://www.ncbi.nlm.nih.gov/pubmed/32365773 http://dx.doi.org/10.3390/ijms21093161

Ejemplares similares

The Phosphodiesterase Type 5 Inhibitor Sildenafil Improves DNA Stability and Redox Homeostasis in Systemic Sclerosis Fibroblasts Exposed to Reactive Oxygen Species
por: Di Luigi, Luigi, et al.
Publicado: (2020)

Sildenafil Counteracts the In Vitro Activation of CXCL-9, CXCL-10 and CXCL-11/CXCR3 Axis Induced by Reactive Oxygen Species in Scleroderma Fibroblasts
por: Antinozzi, Cristina, et al.
Publicado: (2021)

Hydrogen Peroxide Stimulates Dihydrotestosterone Release in C2C12 Myotubes: A New Perspective for Exercise-Related Muscle Steroidogenesis?
por: Antinozzi, Cristina, et al.
Publicado: (2022)

Effect of Tadalafil Administration on Redox Homeostasis and Polyamine Levels in Healthy Men with High Level of Physical Activity
por: Duranti, Guglielmo, et al.
Publicado: (2021)

The Preventive Role of Physical Activity in Systemic Sclerosis: A Cross-Sectional Study on the Correlation with Clinical Parameters and Disease Progression
por: Antinozzi, Cristina, et al.
Publicado: (2022)

Estrogen-Receptor-Positive Breast Cancer in Postmenopausal Women: The Role of Body Composition and Physical Exercise
por: Dimauro, Ivan, et al.
Publicado: (2021)

The p75(NTR)-mediated effect of nerve growth factor in L6C5 myogenic cells
por: de Perini, Alessandra, et al.
Publicado: (2017)

The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence
por: Giannattasio, S., et al.
Publicado: (2018)

Systemic Response of Antioxidants, Heat Shock Proteins, and Inflammatory Biomarkers to Short-Lasting Exercise Training in Healthy Male Subjects
por: Dimauro, Ivan, et al.
Publicado: (2021)

Online Home-Based Physical Activity Counteracts Changes of Redox-Status Biomarkers and Fitness Profiles during Treatment Programs in Postsurgery Female Breast Cancer Patients
por: Moulton, Chantalle, et al.
Publicado: (2023)

Quercetin Supplementation Improves Neuromuscular Function Recovery from Muscle Damage
por: Bazzucchi, Ilenia, et al.
Publicado: (2020)

Oxidative stress responses to a graded maximal exercise test in older adults following explosive-type resistance training()
por: Ceci, Roberta, et al.
Publicado: (2013)

The Effects of Quercetin Supplementation on Eccentric Exercise-Induced Muscle Damage
por: Bazzucchi, Ilenia, et al.
Publicado: (2019)

Moringa oleifera Leaf Extract Upregulates Nrf2/HO-1 Expression and Ameliorates Redox Status in C2C12 Skeletal Muscle Cells
por: Duranti, Guglielmo, et al.
Publicado: (2021)

Quercetin Modulates IGF-I and IGF-II Levels After Eccentric Exercise-Induced Muscle-Damage: A Placebo-Controlled Study
por: Sgrò, Paolo, et al.
Publicado: (2021)

Advantages of Phosphodiesterase Type 5 Inhibitors in the Management of Glucose Metabolism Disorders: A Clinical and Translational Issue
por: Antinozzi, Cristina, et al.
Publicado: (2020)

Moringa oleifera Leaf Extract Protects C2C12 Myotubes against H(2)O(2)-Induced Oxidative Stress
por: Ceci, Roberta, et al.
Publicado: (2022)

The Impact of Spermidine on C2C12 Myoblasts Proliferation, Redox Status and Polyamines Metabolism under H(2)O(2) Exposure
por: Ceci, Roberta, et al.
Publicado: (2022)

Resistance training and redox homeostasis: Correlation with age-associated genomic changes
por: Dimauro, Ivan, et al.
Publicado: (2016)

The Prostacyclin Analogue Iloprost Modulates CXCL10 in Systemic Sclerosis
por: Colasanti, Tania, et al.
Publicado: (2022)

Tadalafil and Steroid Hormones Interactions in Adipose, Bone and Prostate Tissues: Focus on Translational Perspectives
por: Greco, Emanuela Alessandra, et al.
Publicado: (2022)

Alpha B-Crystallin in Muscle Disease Prevention: The Role of Physical Activity
por: Dimauro, Ivan, et al.
Publicado: (2022)

Physical activity in the prevention of human diseases: role of epigenetic modifications
por: Grazioli, Elisa, et al.
Publicado: (2017)

Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition
por: Corinaldesi, Clarissa, et al.
Publicado: (2021)

Association of circulating CXCL10 and CXCL11 with systemic sclerosis
por: Crescioli, Clara, et al.
Publicado: (2018)

Phosphodiesterase Type 5 Inhibitor Sildenafil Decreases the Proinflammatory Chemokine CXCL10 in Human Cardiomyocytes and in Subjects with Diabetic Cardiomyopathy
por: Di Luigi, Luigi, et al.
Publicado: (2016)

IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
por: Adami, Eleonora, et al.
Publicado: (2021)

Il teatro veneto /
por: Lunari, Luigi
Publicado: (2003)

Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
por: Che, Karlhans Fru, et al.
Publicado: (2019)

Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway
por: Ipseiz, Natacha, et al.
Publicado: (2020)

Oxygen–Glucose Deprivation Promoted Fibroblast Senescence and Collagen Expression via IL11
por: Song, Tongtong, et al.
Publicado: (2022)

Exercise, redox homeostasis and the epigenetic landscape
por: Dimauro, Ivan, et al.
Publicado: (2020)

Il pianeta azzurro/
por: Malerba, Luigi 1927-

IL-11 in multiple sclerosis
por: Zhang, Xin, et al.
Publicado: (2015)

Impaired Regulation by IL-35 in Systemic Sclerosis
por: Osuna-Gómez, Rubén, et al.
Publicado: (2023)

Exploratory Analysis in the Differences in Blood Serum and Seminal Plasma of Adipose-Tissue Related Peptides in Obese and Non-Obese Men and Their Correlations With Semen Parameters
por: Antinozzi, Cristina, et al.
Publicado: (2021)

Il prigioniero Canti di prigionia /
por: Dallapiccola, Luigi, 1904-1975
Publicado: (1995)

Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12
por: Barker, S E, et al.
Publicado: (2007)

IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages
por: Scott, Tara E., et al.
Publicado: (2023)

The IL‐1/IL‐1R axis induces greater fibroblast‐derived chemokine release in human papillomavirus‐negative compared to positive oropharyngeal cancer
por: Al‐Sahaf, Sarmad, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qunc4939ssdkocuuvgle93jbd2