Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro

Liver fibrosis is a wound healing process in response to chronic liver injury, which is characterized by the accumulation of extracellular collagen produced by Hepatic Stellate Cells (HSCs). This process involves cell cycle re-entry and proliferation of normally quiescent HSCs controlled by cyclins...

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Detalles Bibliográficos
Autores principales: Hübbers, Anna, Hennings, Julia, Lambertz, Daniela, Haas, Ute, Trautwein, Christian, Nevzorova, Yulia A., Sonntag, Roland, Liedtke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246535/
https://www.ncbi.nlm.nih.gov/pubmed/32380742
http://dx.doi.org/10.3390/ijms21093267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246535/
https://www.ncbi.nlm.nih.gov/pubmed/32380742
http://dx.doi.org/10.3390/ijms21093267

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