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Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro
Liver fibrosis is a wound healing process in response to chronic liver injury, which is characterized by the accumulation of extracellular collagen produced by Hepatic Stellate Cells (HSCs). This process involves cell cycle re-entry and proliferation of normally quiescent HSCs controlled by cyclins...
Autores principales: | Hübbers, Anna, Hennings, Julia, Lambertz, Daniela, Haas, Ute, Trautwein, Christian, Nevzorova, Yulia A., Sonntag, Roland, Liedtke, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246535/ https://www.ncbi.nlm.nih.gov/pubmed/32380742 http://dx.doi.org/10.3390/ijms21093267 |
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