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Investigating Programmed Cell Death and Tumor Invasion in a Three-Dimensional (3D) Microfluidic Model of Glioblastoma

Glioblastoma multiforme (GBM) is a rapidly progressive and deadly form of brain tumor with a median survival rate of ~15 months. GBMs are hard to treat and significantly affect the patient’s physical and cognitive abilities and quality of life. Temozolomide (TMZ)—an alkylating agent that causes DNA...

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Detalles Bibliográficos
Autores principales: Samiei, Ehsan, Seyfoori, Amir, Toyota, Brian, Ghavami, Saeid, Akbari, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246580/
https://www.ncbi.nlm.nih.gov/pubmed/32365781
http://dx.doi.org/10.3390/ijms21093162