Structure–Activity Relationship of RGD-Containing Cyclic Octapeptide and αvβ3 Integrin Allows for Rapid Identification of a New Peptide Antagonist

The αvβ3 integrin, a receptor for many extracellular matrix proteins with RGD-sequence motif, is involved in multiple physiological processes and highly expressed in tumor cells, therefore making it a target for cancer therapy and tumor imaging. Several RGD-containing cyclic octapeptide (named LXW a...

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Detalles Bibliográficos
Autores principales: Silva, Aaron, Xiao, Wenwu, Wang, Yan, Wang, Wei, Chang, Heng Wei, Ames, James B., Lam, Kit S., Zhang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246635/
https://www.ncbi.nlm.nih.gov/pubmed/32349271
http://dx.doi.org/10.3390/ijms21093076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246635/
https://www.ncbi.nlm.nih.gov/pubmed/32349271
http://dx.doi.org/10.3390/ijms21093076

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