Peptide Interference with APP and Tau Association: Relevance to Alzheimer’s Disease Amelioration

The two major proteins involved in Alzheimer’s disease (AD) are the amyloid precursor protein (APP) and Tau. Here, we demonstrate that these two proteins can bind to each other. Four possible peptides APP1 (390–412), APP2 (713–730), Tau1 (19–34) and Tau2 (331–348), were predicted to be involved in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Maron, Ruth, Armony, Gad, Tsoory, Michael, Wilchek, Meir, Frenkel, Dan, Arnon, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246762/
https://www.ncbi.nlm.nih.gov/pubmed/32380752
http://dx.doi.org/10.3390/ijms21093270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246762/
https://www.ncbi.nlm.nih.gov/pubmed/32380752
http://dx.doi.org/10.3390/ijms21093270

Ejemplares similares