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Gold Nanocomplex Strongly Modulates the PI3K/Akt Pathway and Other Pathways in MCF-7 Breast Cancer Cell Line

Conjugating drugs with gold nanoparticles (GNP) is a key strategy in cancer therapy. Herein, the potential inhibition of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, and other pathways of the MCF-7 cell-line, was investigated upon treatment with gold nanorods (GNR) conjugated with a PI3K in...

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Detalles Bibliográficos
Autores principales: Mahmoud, Nouf N., Abuarqoub, Duaa, Zaza, Rand, Sabbah, Dima A., Khalil, Enam A., Abu-Dahab, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246767/
https://www.ncbi.nlm.nih.gov/pubmed/32397063
http://dx.doi.org/10.3390/ijms21093320