The Effects of Human BDH2 on the Cell Cycle, Differentiation, and Apoptosis and Associations with Leukemia Transformation in Myelodysplastic Syndrome

Iron overload is related to leukemia transformation in myelodysplastic syndrome (MDS) patients. Siderophores help to transport iron. Type 2-hydroxybutyrate dehydrogenase (BDH2) is a rate-limiting factor in the biogenesis of siderophores. Using qRT-PCR, we analyze BDH2mRNA expression in the bone marr...

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Detalles Bibliográficos
Autores principales: Yang, Wen-Chi, Lin, Sheng-Fung, Wang, Shu-Chen, Tsai, Wan-Chi, Wu, Chun-Chieh, Wu, Shih-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246807/
https://www.ncbi.nlm.nih.gov/pubmed/32344823
http://dx.doi.org/10.3390/ijms21093033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246807/
https://www.ncbi.nlm.nih.gov/pubmed/32344823
http://dx.doi.org/10.3390/ijms21093033

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