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The Effects of Human BDH2 on the Cell Cycle, Differentiation, and Apoptosis and Associations with Leukemia Transformation in Myelodysplastic Syndrome
Iron overload is related to leukemia transformation in myelodysplastic syndrome (MDS) patients. Siderophores help to transport iron. Type 2-hydroxybutyrate dehydrogenase (BDH2) is a rate-limiting factor in the biogenesis of siderophores. Using qRT-PCR, we analyze BDH2mRNA expression in the bone marr...
Autores principales: | Yang, Wen-Chi, Lin, Sheng-Fung, Wang, Shu-Chen, Tsai, Wan-Chi, Wu, Chun-Chieh, Wu, Shih-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246807/ https://www.ncbi.nlm.nih.gov/pubmed/32344823 http://dx.doi.org/10.3390/ijms21093033 |
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