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Identifying Therapeutic Targets for Spinocerebellar Ataxia Type 3/Machado–Joseph Disease through Integration of Pathological Biomarkers and Therapeutic Strategies

Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a progressive motor disease with no broadly effective treatment. However, most current therapies are based on symptoms rather than the underlying disease mechanisms. In this review, we describe potential therapeutic strategies based...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Shuan, Hong, Zhen-Xiang, Lin, Shinn-Zong, Harn, Horng-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246822/
https://www.ncbi.nlm.nih.gov/pubmed/32357546
http://dx.doi.org/10.3390/ijms21093063