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Comparative Cerebroprotective Potential of d- and l-Carnosine Following Ischemic Stroke in Mice

l-carnosine is an attractive therapeutic agent for acute ischemic stroke based on its robust preclinical cerebroprotective properties and wide therapeutic time window. However, large doses are needed for efficacy because carnosine is rapidly degraded in serum by carnosinases. The need for large dose...

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Detalles Bibliográficos
Autores principales: Jain, Saurabh, Kim, Eun-Sun, Kim, Donghyun, Burrows, David, De Felice, Milena, Kim, Minyeong, Baek, Seung-Hoon, Ali, Ali, Redgrave, Jessica, Doeppner, Thorsten R., Gardner, Iain, Bae, Ok-Nam, Majid, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246848/
https://www.ncbi.nlm.nih.gov/pubmed/32357505
http://dx.doi.org/10.3390/ijms21093053