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Short Exposure to Ethanol Diminishes Caspase-1 and ASC Activation in Human HepG2 Cells In Vitro

This paper discusses how the assembly of pro-caspase-1 and apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) in macromolecular protein complexes, inflammasomes, activates caspase-1. The present study investigates the molecular mechanisms of inflammasome activation...

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Detalles Bibliográficos
Autores principales: Hörauf, Jason-Alexander, Kany, Shinwan, Janicova, Andrea, Xu, Baolin, Vrdoljak, Teodora, Sturm, Ramona, Dunay, Ildiko Rita, Martin, Lukas, Relja, Borna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246869/
https://www.ncbi.nlm.nih.gov/pubmed/32366053
http://dx.doi.org/10.3390/ijms21093196