Inhibition of RNA Helicase Activity Prevents Coxsackievirus B3-Induced Myocarditis in Human iPS Cardiomyocytes

Aims: Coxsackievirus B3 (CVB3) is known to be an important cause of myocarditis and dilated cardiomyopathy. Enterovirus-2C (E2C) is a viral RNA helicase. It inhibits host protein synthesis. Based on these facts, we hypothesize that the inhibition of 2C may suppress virus replication and prevent ente...

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Detalles Bibliográficos
Autores principales: Yun, Soo-Hyeon, Shin, Ha-Hyeon, Ju, Eun-Seon, Lee, You-Jung, Lim, Byung-Kwan, Jeon, Eun-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246926/
https://www.ncbi.nlm.nih.gov/pubmed/32344926
http://dx.doi.org/10.3390/ijms21093041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246926/
https://www.ncbi.nlm.nih.gov/pubmed/32344926
http://dx.doi.org/10.3390/ijms21093041

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