Nifedipine Upregulates ATF6-α, Caspases -12, -3, and -7 Implicating Lipotoxicity-Associated Renal ER Stress

Nifedipine (NF) is reported to have many beneficial effects in antihypertensive therapy. Recently, we found that NF induced lipid accumulation in renal tubular cells. Palmitic acid-induced renal lipotoxicity was found to be partially mediated by endoplasmic reticular (ER) stress, while it can also b...

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Detalles Bibliográficos
Autores principales: Peng, Chiung-Chi, Chen, Chang-Rong, Chen, Chang-Yu, Lin, Yen-Chung, Chen, Kuan-Chou, Peng, Robert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246953/
https://www.ncbi.nlm.nih.gov/pubmed/32365658
http://dx.doi.org/10.3390/ijms21093147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246953/
https://www.ncbi.nlm.nih.gov/pubmed/32365658
http://dx.doi.org/10.3390/ijms21093147

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