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The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62

p62/sequestosome-1 is a scaffolding protein involved in diverse cellular processes such as autophagy, oxidative stress, cell survival and death. It has been identified to interact with atypical protein kinase Cs (aPKCs), linking these kinases to NF-κB activation by tumor necrosis factor α (TNFα). Th...

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Detalles Bibliográficos
Autores principales: Ha, Jihoon, Kim, Minbeom, Seo, Dongyeob, Park, Jin Seok, Lee, Jaewon, Lee, Jinjoo, Park, Seok Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247158/
https://www.ncbi.nlm.nih.gov/pubmed/32354117
http://dx.doi.org/10.3390/ijms21093116