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Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes
Huntington’s disease (HD) is an incurable neurodegenerative disorder caused by CAG trinucleotide expansions in the huntingtin gene. Markers of both systemic and CNS immune activation and inflammation have been widely noted in HD and mouse models of HD. In particular, elevation of the pro-inflammator...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247164/ https://www.ncbi.nlm.nih.gov/pubmed/32448329 http://dx.doi.org/10.1186/s13024-020-00379-3 |