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Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes

Huntington’s disease (HD) is an incurable neurodegenerative disorder caused by CAG trinucleotide expansions in the huntingtin gene. Markers of both systemic and CNS immune activation and inflammation have been widely noted in HD and mouse models of HD. In particular, elevation of the pro-inflammator...

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Detalles Bibliográficos
Autores principales:	Wertz, Mary H., Pineda, S. Sebastian, Lee, Hyeseung, Kulicke, Ruth, Kellis, Manolis, Heiman, Myriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247164/ https://www.ncbi.nlm.nih.gov/pubmed/32448329 http://dx.doi.org/10.1186/s13024-020-00379-3

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