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Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells

BACKGROUND: Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. There are two subtypes, fusion gene-positive RMS (FP-RMS) and fusion gene-negative RMS (FN-RMS), depending on the presence of a fusion gene, either PAX3-FOXO1 or PAX7-FOXO1. These fusion genes are thought to be onco...

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Detalles Bibliográficos
Autores principales: Ouchi, Kazutaka, Miyachi, Mitsuru, Yagyu, Shigeki, Kikuchi, Ken, Kuwahara, Yasumichi, Tsuchiya, Kunihiko, Iehara, Tomoko, Hosoi, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247181/
https://www.ncbi.nlm.nih.gov/pubmed/32489328
http://dx.doi.org/10.1186/s12935-020-01282-z