Effects of the scid mutation on X-ray-induced deletions in the brain and spleen of gpt delta mice

BACKGROUND: DNA-dependent protein kinase (DNA-PK), consisting of a Ku heterodimer (Ku70/80) and a large catalytic subunit (DNA-PKcs), plays an important role in the repair of DNA double-strand breaks via non-homologous end-joining (NHEJ) in mammalian cells. Severe combined immunodeficient (scid) mic...

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Detalles Bibliográficos
Autores principales: Masumura, Kenichi, Yatagai, Fumio, Ochiai, Masako, Nakagama, Hitoshi, Nohmi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247204/
https://www.ncbi.nlm.nih.gov/pubmed/32489484
http://dx.doi.org/10.1186/s41021-020-00158-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247204/
https://www.ncbi.nlm.nih.gov/pubmed/32489484
http://dx.doi.org/10.1186/s41021-020-00158-y

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