The features of polyglutamine regions depend on their evolutionary stability

BACKGROUND: Polyglutamine regions (polyQ) are one of the most studied and prevalent homorepeats in eukaryotes. They have a particular length-dependent codon usage, which relates to a characteristic CAG-slippage mechanism. Pathologically expanded tracts of polyQ are known to form aggregates and are i...

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Detalles Bibliográficos
Autores principales: Mier, Pablo, Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247214/
https://www.ncbi.nlm.nih.gov/pubmed/32448113
http://dx.doi.org/10.1186/s12862-020-01626-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247214/
https://www.ncbi.nlm.nih.gov/pubmed/32448113
http://dx.doi.org/10.1186/s12862-020-01626-3

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