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Protective effects of rolipram on endotoxic cardiac dysfunction via inhibition of the inflammatory response in cardiac fibroblasts

BACKGROUND: Cardiac fibroblasts, regarded as the immunomodulatory hub of the heart, have been thought to play an important role during sepsis-induced cardiomyopathy (SIC). However, the detailed molecular mechanism and targeted therapies for SIC are still lacking. Therefore, we sought to investigate...

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Detalles Bibliográficos
Autores principales: Ji, Jingjing, Liu, Zhifeng, Hong, Xinxin, Liu, Zheying, Gao, Jinghua, Liu, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247226/
https://www.ncbi.nlm.nih.gov/pubmed/32448150
http://dx.doi.org/10.1186/s12872-020-01529-7