Novel Antibodies Targeting MUC1-C Showed Anti-Metastasis and Growth-Inhibitory Effects on Human Breast Cancer Cells

Mucin1 (MUC1) is aberrantly glycosylated and overexpressed in various cancers, and it plays a crucial role in cancerogenesis. MUC1 is a type I membranous protein composed of α and β subunits. MUC1-α can be cleaved in cancers, exposing MUC1-β (MUC1-C). MUC1-C is involved with multiple cancer cellular...

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Detalles Bibliográficos
Autores principales: Kim, Min Jung, Choi, Jong Rip, Tae, Nara, Wi, Tae Min, Kim, Kristine M., Kim, Dae Hee, Lee, Eung Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247325/
https://www.ncbi.nlm.nih.gov/pubmed/32380650
http://dx.doi.org/10.3390/ijms21093258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247325/
https://www.ncbi.nlm.nih.gov/pubmed/32380650
http://dx.doi.org/10.3390/ijms21093258

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