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Reactions of Plasmodium falciparum Ferredoxin:NADP(+) Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study

Ferredoxin:NADP(+) oxidoreductase from Plasmodium falciparum (PfFNR) catalyzes the NADPH-dependent reduction of ferredoxin (PfFd), which provides redox equivalents for the biosynthesis of isoprenoids and fatty acids in the apicoplast. Like other flavin-dependent electrontransferases, PfFNR is a pote...

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Detalles Bibliográficos
Autores principales: Lesanavičius, Mindaugas, Aliverti, Alessandro, Šarlauskas, Jonas, Čėnas, Narimantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247349/
https://www.ncbi.nlm.nih.gov/pubmed/32370303
http://dx.doi.org/10.3390/ijms21093234