SARS Unique Domain (SUD) of Severe Acute Respiratory Syndrome Coronavirus Induces NLRP3 Inflammasome-Dependent CXCL10-Mediated Pulmonary Inflammation

Severe acute respiratory syndrome–associated coronavirus (SARS-CoV) initiates the cytokine/chemokine storm-mediated lung injury. The SARS-CoV unique domain (SUD) with three macrodomains (N, M, and C), showing the G-quadruplex binding activity, was examined the possible role in SARS pathogenesis in t...

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Detalles Bibliográficos
Autores principales: Chang, Young-Sheng, Ko, Bo-Han, Ju, Jyh-Cherng, Chang, Hsin-Hou, Huang, Su-Hua, Lin, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247444/
https://www.ncbi.nlm.nih.gov/pubmed/32365944
http://dx.doi.org/10.3390/ijms21093179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247444/
https://www.ncbi.nlm.nih.gov/pubmed/32365944
http://dx.doi.org/10.3390/ijms21093179

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