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SARS Unique Domain (SUD) of Severe Acute Respiratory Syndrome Coronavirus Induces NLRP3 Inflammasome-Dependent CXCL10-Mediated Pulmonary Inflammation
Severe acute respiratory syndrome–associated coronavirus (SARS-CoV) initiates the cytokine/chemokine storm-mediated lung injury. The SARS-CoV unique domain (SUD) with three macrodomains (N, M, and C), showing the G-quadruplex binding activity, was examined the possible role in SARS pathogenesis in t...
Autores principales: | Chang, Young-Sheng, Ko, Bo-Han, Ju, Jyh-Cherng, Chang, Hsin-Hou, Huang, Su-Hua, Lin, Cheng-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247444/ https://www.ncbi.nlm.nih.gov/pubmed/32365944 http://dx.doi.org/10.3390/ijms21093179 |
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