In silico analysis on the functional and structural impact of Rad50 mutations involved in DNA strand break repair

BACKGROUND: DNA double strand break repair is important to preserve the fidelity of our genetic makeup after DNA damage. Rad50 is one of the components in MRN complex important for DNA repair mechanism. Rad50 mutations can lead to microcephaly, mental retardation and growth retardation in human. How...

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Detalles Bibliográficos
Autores principales: Remali, Juwairiah, Aizat, Wan Mohd, Ng, Chyan Leong, Lim, Yi Chieh, Mohamed-Hussein, Zeti-Azura, Fazry, Shazrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247530/
https://www.ncbi.nlm.nih.gov/pubmed/32509463
http://dx.doi.org/10.7717/peerj.9197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247530/
https://www.ncbi.nlm.nih.gov/pubmed/32509463
http://dx.doi.org/10.7717/peerj.9197

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