The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens

Regulatory T cells (Tregs) are essential for the maintenance of tolerance to self and non-self through cell-intrinsic and cell-extrinsic mechanisms. Peripheral Tregs survival and clonal expansion largely depend on IL-2 and access to co-stimulatory signals such as CD28. Engagement of tumor necrosis f...

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Detalles Bibliográficos
Autores principales: Rodriguez-Barbosa, Jose-Ignacio, Schneider, Pascal, Graca, Luis, Bühler, Leo, Perez-Simon, Jose-Antonio, del Rio, Maria-Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247540/
https://www.ncbi.nlm.nih.gov/pubmed/32397343
http://dx.doi.org/10.3390/ijms21093347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247540/
https://www.ncbi.nlm.nih.gov/pubmed/32397343
http://dx.doi.org/10.3390/ijms21093347

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