An α5 GABAA Receptor Inverse Agonist, α5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder for which no cognition-restoring therapies exist. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. Increasing evidence suggests a remodeling of the GABAergic system in AD, which might represen...

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Detalles Bibliográficos
Autores principales: Vinnakota, Chitra, Govindpani, Karan, Tate, Warren Perry, Peppercorn, Katie, Anekal, Praju Vikas, Waldvogel, Henry John, Faull, Richard Lewis Maxwell, Kwakowsky, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247548/
https://www.ncbi.nlm.nih.gov/pubmed/32384683
http://dx.doi.org/10.3390/ijms21093284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247548/
https://www.ncbi.nlm.nih.gov/pubmed/32384683
http://dx.doi.org/10.3390/ijms21093284

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