Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation in the gastrointestinal tract. Biological therapeutics and orally available small molecules like tofacitinib (a JAK inhibitor) have been developed to treat IBD, but half of the patients treated with these drugs fail to achieve sust...

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Detalles Bibliográficos
Autores principales: Gurung, Pallavi, Dahal, Sadan, Chaudhary, Prakash, Guragain, Diwakar, Karmacharya, Ujjwala, Kim, Jung-Ae, Jeong, Byeong-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247564/
https://www.ncbi.nlm.nih.gov/pubmed/32365634
http://dx.doi.org/10.3390/ijms21093145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247564/
https://www.ncbi.nlm.nih.gov/pubmed/32365634
http://dx.doi.org/10.3390/ijms21093145

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