Repurposing Tyrosine Kinase Inhibitors to Overcome Multidrug Resistance in Cancer: A Focus on Transporters and Lysosomal Sequestration

Tyrosine kinase inhibitors (TKIs) are being increasingly used to treat various malignancies. Although they were designed to target aberrant tyrosine kinases, they are also intimately linked with the mechanisms of multidrug resistance (MDR) in cancer cells. MDR-related solute carrier (SLC) and ATB-bi...

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Detalles Bibliográficos
Autores principales: Krchniakova, Maria, Skoda, Jan, Neradil, Jakub, Chlapek, Petr, Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247577/
https://www.ncbi.nlm.nih.gov/pubmed/32365759
http://dx.doi.org/10.3390/ijms21093157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247577/
https://www.ncbi.nlm.nih.gov/pubmed/32365759
http://dx.doi.org/10.3390/ijms21093157

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