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Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals

To diagnose and treat early-stage (preclinical) Alzheimer’s disease (AD) patients, we need body-fluid-based biomarkers that reflect the processes that occur in this stage, but current knowledge on associated processes is lacking. As human studies on (possible) onset and early-stage AD would be extre...

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Detalles Bibliográficos
Autores principales: Qin, Tian, Prins, Samantha, Groeneveld, Geert Jan, Van Westen, Gerard, de Vries, Helga E., Wong, Yin Cheong, Bischoff, Luc J.M., de Lange, Elizabeth C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247586/
https://www.ncbi.nlm.nih.gov/pubmed/32365768
http://dx.doi.org/10.3390/ijms21093158