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Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals
To diagnose and treat early-stage (preclinical) Alzheimer’s disease (AD) patients, we need body-fluid-based biomarkers that reflect the processes that occur in this stage, but current knowledge on associated processes is lacking. As human studies on (possible) onset and early-stage AD would be extre...
Autores principales: | Qin, Tian, Prins, Samantha, Groeneveld, Geert Jan, Van Westen, Gerard, de Vries, Helga E., Wong, Yin Cheong, Bischoff, Luc J.M., de Lange, Elizabeth C.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247586/ https://www.ncbi.nlm.nih.gov/pubmed/32365768 http://dx.doi.org/10.3390/ijms21093158 |
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