Gene-Wise Burden of Coding Variants Correlates to Noncoding Pharmacogenetic Risk Variants

Genetic variability can modulate individual drug responses. A significant portion of pharmacogenetic variants reside in the noncoding genome yet it is unclear if the noncoding variants directly influence protein function and expression or are present on a haplotype including a functionally relevant...

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Detalles Bibliográficos
Autores principales: Park, Jihye, Lee, Soo Youn, Baik, Su Youn, Park, Chan Hee, Yoon, Jun Hee, Ryu, Brian Y., Kim, Ju Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247590/
https://www.ncbi.nlm.nih.gov/pubmed/32349395
http://dx.doi.org/10.3390/ijms21093091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247590/
https://www.ncbi.nlm.nih.gov/pubmed/32349395
http://dx.doi.org/10.3390/ijms21093091

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