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Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures

Mutations in actins have been linked to several developmental diseases. Their occurrence across different cancers has, however, not been investigated. Using the cBioPortal database we show that human actins are infrequently mutated in patient samples of various cancers types. Nevertheless, ranking t...

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Detalles Bibliográficos
Autores principales: Witjes, Laura, Van Troys, Marleen, Verhasselt, Bruno, Ampe, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247664/
https://www.ncbi.nlm.nih.gov/pubmed/32349449
http://dx.doi.org/10.3390/ijms21093093