Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1α

Combined androgen blockade using bicalutamide (Bic) is a therapeutic choice for treating prostate cancer (PCa). However, even at regular clinical dosages, Bic frequently shows adverse effects associated with cardiovascular and renal damage. Previously, we found that Bic selectively damaged mesangial...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Kuan-Chou, Chen, Chang-Rong, Chen, Chang-Yu, Tzou, Kai-Yi, Peng, Chiung-Chi, Peng, Robert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247665/
https://www.ncbi.nlm.nih.gov/pubmed/32403414
http://dx.doi.org/10.3390/ijms21093400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247665/
https://www.ncbi.nlm.nih.gov/pubmed/32403414
http://dx.doi.org/10.3390/ijms21093400

Ejemplares similares