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The Cannabinoid Receptor CB1 Stabilizes Sperm Chromatin Condensation Status During Epididymal Transit by Promoting Disulphide Bond Formation

The cannabinoid receptor CB1 regulates differentiation of spermatids. We recently characterized spermatozoa from caput epididymis of CB1-knock-out mice and identified a considerable number of sperm cells with chromatin abnormality such as elevated histone content and poorly condensed chromatin. In t...

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Detalles Bibliográficos
Autores principales: Chioccarelli, Teresa, Manfrevola, Francesco, Porreca, Veronica, Fasano, Silvia, Altucci, Lucia, Pierantoni, Riccardo, Cobellis, Gilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247701/
https://www.ncbi.nlm.nih.gov/pubmed/32354121
http://dx.doi.org/10.3390/ijms21093117