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The Cannabinoid Receptor CB1 Stabilizes Sperm Chromatin Condensation Status During Epididymal Transit by Promoting Disulphide Bond Formation
The cannabinoid receptor CB1 regulates differentiation of spermatids. We recently characterized spermatozoa from caput epididymis of CB1-knock-out mice and identified a considerable number of sperm cells with chromatin abnormality such as elevated histone content and poorly condensed chromatin. In t...
Autores principales: | Chioccarelli, Teresa, Manfrevola, Francesco, Porreca, Veronica, Fasano, Silvia, Altucci, Lucia, Pierantoni, Riccardo, Cobellis, Gilda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247701/ https://www.ncbi.nlm.nih.gov/pubmed/32354121 http://dx.doi.org/10.3390/ijms21093117 |
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