Interactions of the Lysosomotropic Detergent O-Methyl-Serine Dodecylamide Hydrochloride (MSDH) with Lipid Bilayer Membranes—Implications for Cell Toxicity

O-methyl-serine dodecylamine hydrochloride (MSDH) is a detergent that accumulates selectively in lysosomes, a so-called lysosomotropic detergent, with unexpected chemical properties. At physiological pH, it spontaneously forms vesicles, which disassemble into small aggregates (probably micelles) bel...

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Detalles Bibliográficos
Autores principales: Villamil Giraldo, Ana-Maria, Eriksson, Ida, Wennmalm, Stefan, Fyrner, Timmy, Ederth, Thomas, Öllinger, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247706/
https://www.ncbi.nlm.nih.gov/pubmed/32365555
http://dx.doi.org/10.3390/ijms21093136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247706/
https://www.ncbi.nlm.nih.gov/pubmed/32365555
http://dx.doi.org/10.3390/ijms21093136

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