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A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology

Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus spp., is hindered by an incomplete knowledge of th...

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Detalles Bibliográficos
Autores principales: Sanchez-Muñoz, Raul, Perez-Mata, Edgar, Almagro, Lorena, Cusido, Rosa M., Bonfill, Mercedes, Palazon, Javier, Moyano, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247824/
https://www.ncbi.nlm.nih.gov/pubmed/32528936
http://dx.doi.org/10.3389/fbioe.2020.00410